He was a descendant of the Octavii Rufi (through Gaius Octavius), Julii Caesares (through Julia Minor and Julia Antonia), and the Claudii Nerones (through Nero Claudius Drusus); he was a great-nephew of Augustus through his full sister Octavia Minor, a nephew of Tiberius through his father Drusus, Tiberius' brother, an uncle of Caligula and finally a great-uncle of Nero through Caligula's father and Nero's grandfather Germanicus, his brother.
Claudius was born on 1 August 10 BC at Lugdunum (modern Lyon, France). His mother, Antonia, may have had two other children who died young.
He was seen as vulnerable throughout his reign, particularly by elements of the nobility.
A member of the Julio-Claudian dynasty, he was the son of Drusus and Antonia Minor.
In either case, it was far too early for such an account, and may have only served to remind Augustus that Claudius was Antony's descendant.
His mother and grandmother quickly put a stop to it, and this may have convinced them that Claudius was not fit for public office.
Claudius was then left to be raised by his mother, who never remarried.
When Claudius' disability became evident, the relationship with his family turned sour.
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His maternal grandparents were Mark Antony and Octavia Minor, Augustus' sister, and he was therefore the great-great grandnephew of Gaius Julius Caesar.